Moreover, the self-induced fit is standard operating procedure in the laboratory. Allow me to quote Lewis Thomas, who, in his The Lives Of a Cell, describes the difference between applied science and basic research. After pointing out how applied science deals only with the precise application of known facts, he writes on page 138:

 

In basic research, everything is just the opposite. What you need at the outset is a high degree of uncertainty; otherwise it isn't likely to be an important problem. You start with an incomplete roster of facts, characterized by their ambiguity; often the problem consists of discovering the connections between unrelated pieces of information. You must plan experiments on the basis of probability, even bare possibility, rather than certainty. If an experiment turns out precisely as predicted, this can be very nice, but it is only a great event if at the same time it is a surprise. You can measure the quality of the work by the intensity of astonishment. The surprise can be because it did turn out as predicted (in some lines of research, 1 per cent is accepted as a high yield), or it can be a confoundment because the prediction was wrong and something totally unexpected turned up, changing the look of the problem and requiring a new kind of protocol. Either way, you win...

 

Isn't it reasonable to conclude that the defining distinction between applied science and basic research is the same as that between prose and poetry? Isn't it likewise reasonable to conclude that the making of basic science is very much the same as the making of poetry?

 

In a real way I, too, work in a laboratory. Every day at 9 a.m. I arrive at a table in the local coffee shop, open a dog-eared book of photographs, open a text, and begin mixing all my materials together to find something new.

 

For the famous Walker Evans photograph depicting a migrant's wife, I began:

 

Walker Evans Farmer's wife
Tough life, mouth closed, no teeth? Sorrow? Not too bad looking. Plain dress

 

This description went on and on until I felt I had drained the photograph of all its ideas. I then read the chapter entitled, "On Various Words," from The Lives of a Cell. Photograph still in view, I then wrote down ideas from Dr. Thomas's text. I began:

 

Wordsmdash;bricks and mortar
Writing is an art, compulsively adding to,
building the ant hill,
certain to be a cliché.